| 03/05/2022 | Mavricks | Mustangs | 4:30PM - 6:15PM | Macedonia / 1 | |
| 03/14/2022 | 1402 Brewers | 1401 Braves | 6:00PM - 7:45PM | South Cherokee Baseball / SC Field 8 | Rescheduled |
| 03/15/2022 | Mustangs | ECB | 7:30PM - 9:15PM | East Cherokee / 1 | |
| 03/19/2022 | ECB | 1401 Braves | 10:00AM - 11:45AM | South Cherokee Baseball / SC Field 8 | |
| 03/20/2022 | Mavricks | 1402 Brewers | 3:00PM - 4:45PM | South Cherokee Baseball / SC Field 8 | Rescheduled |
| 03/24/2022 | Mustangs | Mavricks | 7:45PM - 9:30PM | Macedonia / 1 | |
| 03/25/2022 | ECB | 1402 Brewers | 6:30PM - 8:15PM | South Cherokee Baseball / SC Field 8 | |
| 03/26/2022 | 1401 Braves | Mavricks | 6:45PM - 8:30PM | Macedonia / 1 | |
| 03/29/2022 | 1402 Brewers | ECB | 7:45PM - 9:30PM | East Cherokee / 1 | |
| 04/01/2022 | Mavricks | 1401 Braves | 6:30PM - 8:15PM | South Cherokee Baseball / SC Field 8 | |
| 04/01/2022 | 1402 Brewers | Mustangs | 7:30PM - 9:15PM | Macedonia / 1 | |
| 04/11/2022 | Mavricks | Mustangs | 7:45PM - 9:30PM | Macedonia / 1 | |
| 04/12/2022 | 1402 Brewers | ECB | 7:45PM - 9:30PM | East Cherokee / 1 | |
| 04/16/2022 | 1402 Brewers | Mavricks | 9:00AM - 11:45AM | Macedonia / 1 | |
| 04/21/2022 | 1401 Braves | Mustangs | 7:30PM - 9:15PM | Macedonia / 1 | |
| 04/22/2022 | ECB | Mavricks | 7:30PM - 9:15PM | Macedonia / 1 | |
| 04/23/2022 | 1401 Braves | 1402 Brewers | 10:00AM - 11:45AM | South Cherokee Baseball / SC Field 8 | |
| 04/25/2022 | Mustangs | 1401 Braves | 6:00PM - 7:45PM | South Cherokee Baseball / SC Field 8 | |
| 04/28/2022 | ECB | Mavricks | 7:30PM - 9:15PM | Macedonia / 1 | |
| 04/30/2022 | Mustangs | 1402 Brewers | 10:00AM - 11:45AM | South Cherokee Baseball / SC Field 8 | |
| 04/30/2022 | 1401 Braves | ECB | 12:00PM - 1:45PM | South Cherokee Baseball / SC Field 8 | |
| 05/05/2022 | ECB | Mustangs | 7:30PM - 9:15PM | Macedonia / 1 | |
| 05/07/2022 | Mavricks | ECB | 10:00AM - 11:45AM | East Cherokee / 1 | |
| 05/07/2022 | 1401 Braves | 1402 Brewers | 10:00AM - 11:45AM | South Cherokee Baseball / SC Field 8 | |
| 05/07/2022 | Mustangs | 1401 Braves | 12:00PM - 1:45PM | South Cherokee Baseball / SC Field 8 | |